Mitochondrial Functions, Energy Metabolism and Protein Glycosylation are Interconnected Processes Mediating Resistance to Bortezomib in Multiple Myeloma Cells

The proteasome inhibitor bortezomib (BTZ) has emerged as an effective drug for the treatment of multiple myeloma even though many patients relapse from BTZ therapy. The present study investigated the metabolic pathways underlying the acquisition of bortezomib resistance in multiple myeloma. We used...

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Detalles Bibliográficos
Autores principales: Tibullo, Daniele, Giallongo, Cesarina, Romano, Alessandra, Vicario, Nunzio, Barbato, Alessandro, Puglisi, Fabrizio, Parenti, Rosalba, Amorini, Angela Maria, Saab, Miriam Wissam, Tavazzi, Barbara, Mangione, Renata, Brundo, Maria Violetta, Lazzarino, Giacomo, Palumbo, Giuseppe Alberto, Li Volti, Giovanni, Di Raimondo, Francesco, Lazzarino, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277183/
https://www.ncbi.nlm.nih.gov/pubmed/32365811
http://dx.doi.org/10.3390/biom10050696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277183/
https://www.ncbi.nlm.nih.gov/pubmed/32365811
http://dx.doi.org/10.3390/biom10050696

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