In Vitro Activity of a Novel Siderophore-Cephalosporin, GT-1 and Serine-Type β-Lactamase Inhibitor, GT-055, against Escherichia coli, Klebsiella pneumoniae and Acinetobacter spp. Panel Strains

This study investigates GT-1 (also known as LCB10-0200), a novel-siderophore cephalosporin, inhibited multidrug-resistant (MDR) Gram-negative pathogen, via a Trojan horse strategy exploiting iron-uptake systems. We investigated GT-1 activity and the role of siderophore uptake systems, and the combin...

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Detalles Bibliográficos
Autores principales: Nguyen, Le Phuong, Pinto, Naina Adren, Vu, Thao Nguyen, Lee, Hyunsook, Cho, Young Lag, Byun, Jung-Hyun, D’Souza, Roshan, Yong, Dongeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277296/
https://www.ncbi.nlm.nih.gov/pubmed/32443875
http://dx.doi.org/10.3390/antibiotics9050267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277296/
https://www.ncbi.nlm.nih.gov/pubmed/32443875
http://dx.doi.org/10.3390/antibiotics9050267

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