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Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients

INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study w...

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Autores principales: Zaidi, Nasir Raza, Gilani, Syed Amir, Mehboob, Riffat, Waseem, Humaira, Hassan, Amber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277461/
https://www.ncbi.nlm.nih.gov/pubmed/32529110
http://dx.doi.org/10.5114/amsad.2020.95651
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author Zaidi, Nasir Raza
Gilani, Syed Amir
Mehboob, Riffat
Waseem, Humaira
Hassan, Amber
author_facet Zaidi, Nasir Raza
Gilani, Syed Amir
Mehboob, Riffat
Waseem, Humaira
Hassan, Amber
author_sort Zaidi, Nasir Raza
collection PubMed
description INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study was to assess the diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients. MATERIAL AND METHODS: This was a case control study, including 100 cases and the same number of controls. Patients with positive angiographic findings and chest pain were considered as cases and those without as negative. Duplex carotid ultrasound was used to detect intima-media thickness (IMT). B-mode real-time ultrasonic images were obtained with a 7 MHz transducer. An intima media thickness of 0.6 mm was considered as being without plaque. RESULTS: The angiographic findings were single-vessel disease, double-vessel disease, and triple-vessel disease in 18%, 11.5%, and 20.5% of cases, respectively, while there were no findings in controls. There was plaque formation in 14.5% and calcification in 12% of the cases. Sensitivity of B-mode ultrasonography was found to be 78%, specificity 75%, positive predictive value 75.72%, and negative predictive value 77.31%. CONCLUSIONS: Carotid ultrasonography can be utilised as a valuable screening tool due to having several advantages, including ease of application, reproducibility, low cost, and strong correlation with atherosclerosis.
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spelling pubmed-72774612020-06-10 Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients Zaidi, Nasir Raza Gilani, Syed Amir Mehboob, Riffat Waseem, Humaira Hassan, Amber Arch Med Sci Atheroscler Dis Clinical Research INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study was to assess the diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients. MATERIAL AND METHODS: This was a case control study, including 100 cases and the same number of controls. Patients with positive angiographic findings and chest pain were considered as cases and those without as negative. Duplex carotid ultrasound was used to detect intima-media thickness (IMT). B-mode real-time ultrasonic images were obtained with a 7 MHz transducer. An intima media thickness of 0.6 mm was considered as being without plaque. RESULTS: The angiographic findings were single-vessel disease, double-vessel disease, and triple-vessel disease in 18%, 11.5%, and 20.5% of cases, respectively, while there were no findings in controls. There was plaque formation in 14.5% and calcification in 12% of the cases. Sensitivity of B-mode ultrasonography was found to be 78%, specificity 75%, positive predictive value 75.72%, and negative predictive value 77.31%. CONCLUSIONS: Carotid ultrasonography can be utilised as a valuable screening tool due to having several advantages, including ease of application, reproducibility, low cost, and strong correlation with atherosclerosis. Termedia Publishing House 2020-05-27 /pmc/articles/PMC7277461/ /pubmed/32529110 http://dx.doi.org/10.5114/amsad.2020.95651 Text en Copyright © 2020 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Clinical Research
Zaidi, Nasir Raza
Gilani, Syed Amir
Mehboob, Riffat
Waseem, Humaira
Hassan, Amber
Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title_full Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title_fullStr Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title_full_unstemmed Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title_short Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
title_sort diagnostic accuracy of carotid intima media thickness by b-mode ultrasonography in coronary artery disease patients
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277461/
https://www.ncbi.nlm.nih.gov/pubmed/32529110
http://dx.doi.org/10.5114/amsad.2020.95651
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