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Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients
INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277461/ https://www.ncbi.nlm.nih.gov/pubmed/32529110 http://dx.doi.org/10.5114/amsad.2020.95651 |
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author | Zaidi, Nasir Raza Gilani, Syed Amir Mehboob, Riffat Waseem, Humaira Hassan, Amber |
author_facet | Zaidi, Nasir Raza Gilani, Syed Amir Mehboob, Riffat Waseem, Humaira Hassan, Amber |
author_sort | Zaidi, Nasir Raza |
collection | PubMed |
description | INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study was to assess the diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients. MATERIAL AND METHODS: This was a case control study, including 100 cases and the same number of controls. Patients with positive angiographic findings and chest pain were considered as cases and those without as negative. Duplex carotid ultrasound was used to detect intima-media thickness (IMT). B-mode real-time ultrasonic images were obtained with a 7 MHz transducer. An intima media thickness of 0.6 mm was considered as being without plaque. RESULTS: The angiographic findings were single-vessel disease, double-vessel disease, and triple-vessel disease in 18%, 11.5%, and 20.5% of cases, respectively, while there were no findings in controls. There was plaque formation in 14.5% and calcification in 12% of the cases. Sensitivity of B-mode ultrasonography was found to be 78%, specificity 75%, positive predictive value 75.72%, and negative predictive value 77.31%. CONCLUSIONS: Carotid ultrasonography can be utilised as a valuable screening tool due to having several advantages, including ease of application, reproducibility, low cost, and strong correlation with atherosclerosis. |
format | Online Article Text |
id | pubmed-7277461 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-72774612020-06-10 Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients Zaidi, Nasir Raza Gilani, Syed Amir Mehboob, Riffat Waseem, Humaira Hassan, Amber Arch Med Sci Atheroscler Dis Clinical Research INTRODUCTION: Cardiovascular diseases (CVD) are the main cause of premature deaths worldwide, and atherosclerosis (AS) is a major risk factor associated with them. B-mode ultrasound is a well-validated research tool that has been translated increasingly into clinical practice. The aim of the study was to assess the diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients. MATERIAL AND METHODS: This was a case control study, including 100 cases and the same number of controls. Patients with positive angiographic findings and chest pain were considered as cases and those without as negative. Duplex carotid ultrasound was used to detect intima-media thickness (IMT). B-mode real-time ultrasonic images were obtained with a 7 MHz transducer. An intima media thickness of 0.6 mm was considered as being without plaque. RESULTS: The angiographic findings were single-vessel disease, double-vessel disease, and triple-vessel disease in 18%, 11.5%, and 20.5% of cases, respectively, while there were no findings in controls. There was plaque formation in 14.5% and calcification in 12% of the cases. Sensitivity of B-mode ultrasonography was found to be 78%, specificity 75%, positive predictive value 75.72%, and negative predictive value 77.31%. CONCLUSIONS: Carotid ultrasonography can be utilised as a valuable screening tool due to having several advantages, including ease of application, reproducibility, low cost, and strong correlation with atherosclerosis. Termedia Publishing House 2020-05-27 /pmc/articles/PMC7277461/ /pubmed/32529110 http://dx.doi.org/10.5114/amsad.2020.95651 Text en Copyright © 2020 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Clinical Research Zaidi, Nasir Raza Gilani, Syed Amir Mehboob, Riffat Waseem, Humaira Hassan, Amber Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title | Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title_full | Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title_fullStr | Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title_full_unstemmed | Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title_short | Diagnostic accuracy of carotid intima media thickness by B-mode ultrasonography in coronary artery disease patients |
title_sort | diagnostic accuracy of carotid intima media thickness by b-mode ultrasonography in coronary artery disease patients |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277461/ https://www.ncbi.nlm.nih.gov/pubmed/32529110 http://dx.doi.org/10.5114/amsad.2020.95651 |
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