Peroxisome Proliferator Activator Receptor Gamma Coactivator-1α Overexpression in Amyotrophic Lateral Sclerosis: A Tale of Two Transgenics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder manifesting with upper and lower neuron loss, leading to impairments in voluntary muscle function and atrophy. Mitochondrial dysfunction in metabolism and morphology have been implicated in the pathogenesis of ALS, inclu...

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Detalles Bibliográficos
Autores principales: Varghese, Merina, Zhao, Wei, Trageser, Kyle J., Pasinetti, Giulio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277592/
https://www.ncbi.nlm.nih.gov/pubmed/32414179
http://dx.doi.org/10.3390/biom10050760

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