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The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives

The NRF2/KEAP1 pathway is a fundamental signaling cascade that controls multiple cytoprotective responses through the induction of a complex transcriptional program that ultimately renders cancer cells resistant to oxidative, metabolic and therapeutic stress. Interestingly, accumulating evidence in...

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Detalles Bibliográficos
Autores principales: Panieri, Emiliano, Telkoparan-Akillilar, Pelin, Suzen, Sibel, Saso, Luciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277620/
https://www.ncbi.nlm.nih.gov/pubmed/32443774
http://dx.doi.org/10.3390/biom10050791