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The NRF2/KEAP1 Axis in the Regulation of Tumor Metabolism: Mechanisms and Therapeutic Perspectives
The NRF2/KEAP1 pathway is a fundamental signaling cascade that controls multiple cytoprotective responses through the induction of a complex transcriptional program that ultimately renders cancer cells resistant to oxidative, metabolic and therapeutic stress. Interestingly, accumulating evidence in...
Autores principales: | Panieri, Emiliano, Telkoparan-Akillilar, Pelin, Suzen, Sibel, Saso, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277620/ https://www.ncbi.nlm.nih.gov/pubmed/32443774 http://dx.doi.org/10.3390/biom10050791 |
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