On the Electrochemical Detection of Alpha-Fetoprotein Using Aptamers: DNA Isothermal Amplification Strategies to Improve the Performance of Weak Aptamers

Affinity characterization is essential to develop reliable aptamers for tumor biomarker detection. For alpha-fetoprotein (AFP), a biomarker of hepatocellular carcinoma (HCC), two DNA aptamers were described with very different affinity. In this work, we estimate the dissociation constant of both of...

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Detalles Bibliográficos
Autores principales: Lorenzo-Gómez, Ramón, González-Robles, Daniel, Miranda-Castro, Rebeca, de-los-Santos-Álvarez, Noemí, Lobo-Castañón, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277757/
https://www.ncbi.nlm.nih.gov/pubmed/32365872
http://dx.doi.org/10.3390/bios10050046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277757/
https://www.ncbi.nlm.nih.gov/pubmed/32365872
http://dx.doi.org/10.3390/bios10050046

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