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Palladium-catalyzed regio- and stereoselective synthesis of aryl and 3-indolyl-substituted 4-methylene-3,4-dihydroisoquinolin-1(2H)-ones

Cascade cyclocarbopalladation of the readily available aryl/alkyl-substituted propargylic amides containing an aryl iodide moiety, followed by Suzuki–Miyaura coupling with arylboronic acids, allowed an efficient regio- and stereoselective synthesis of tetrasubstituted 4-methylene-3,4-dihydroisoquino...

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Detalles Bibliográficos
Autores principales: Nori, Valeria, Arcadi, Antonio, Carlone, Armando, Marinelli, Fabio, Chiarini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277796/
https://www.ncbi.nlm.nih.gov/pubmed/32550923
http://dx.doi.org/10.3762/bjoc.16.95