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The Israeli Phage Bank (IPB)

A key element in phage therapy is the establishment of large phage collections, termed herein “banks”, where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical pha...

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Detalles Bibliográficos
Autores principales: Yerushalmy, Ortal, Khalifa, Leron, Gold, Naama, Rakov, Chani, Alkalay-Oren, Sivan, Adler, Karen, Ben-Porat, Shira, Kraitman, Reut, Gronovich, Niv, Shulamit Ginat, Kerem, Abdalrhman, Mohanad, Coppenhagen-Glazer, Shunit, Nir-Paz, Ran, Hazan, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277922/
https://www.ncbi.nlm.nih.gov/pubmed/32455557
http://dx.doi.org/10.3390/antibiotics9050269
Descripción
Sumario:A key element in phage therapy is the establishment of large phage collections, termed herein “banks”, where many well-characterized phages, ready to be used in the clinic, are stored. These phage banks serve for both research and clinical purposes. Phage banks are also a key element in clinical phage microbiology, the prior treatment matching of phages and antibiotics to specific bacterial targets. A worldwide network of phage banks can promote a phage-based solution for any isolated bacteria. Herein, we describe the Israeli Phage Bank (IPB) established in the Hebrew University, Jerusalem, which currently has over 300 phages matching 16 bacteria, mainly pathogens. The phage bank is constantly isolating new phages and developing methods for phage isolation and characterization. The information on the phages and bacteria stored in the bank is available online.