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Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application

Malaria is a life-threatening disease that is spread by the Plasmodium parasites. It is detected by trained microscopists who analyze microscopic blood smear images. Modern deep learning techniques may be used to do this analysis automatically. The need for the trained personnel can be greatly reduc...

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Autores principales: Fuhad, K. M. Faizullah, Tuba, Jannat Ferdousey, Sarker, Md. Rabiul Ali, Momen, Sifat, Mohammed, Nabeel, Rahman, Tanzilur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277980/
https://www.ncbi.nlm.nih.gov/pubmed/32443868
http://dx.doi.org/10.3390/diagnostics10050329
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author Fuhad, K. M. Faizullah
Tuba, Jannat Ferdousey
Sarker, Md. Rabiul Ali
Momen, Sifat
Mohammed, Nabeel
Rahman, Tanzilur
author_facet Fuhad, K. M. Faizullah
Tuba, Jannat Ferdousey
Sarker, Md. Rabiul Ali
Momen, Sifat
Mohammed, Nabeel
Rahman, Tanzilur
author_sort Fuhad, K. M. Faizullah
collection PubMed
description Malaria is a life-threatening disease that is spread by the Plasmodium parasites. It is detected by trained microscopists who analyze microscopic blood smear images. Modern deep learning techniques may be used to do this analysis automatically. The need for the trained personnel can be greatly reduced with the development of an automatic accurate and efficient model. In this article, we propose an entirely automated Convolutional Neural Network (CNN) based model for the diagnosis of malaria from the microscopic blood smear images. A variety of techniques including knowledge distillation, data augmentation, Autoencoder, feature extraction by a CNN model and classified by Support Vector Machine (SVM) or K-Nearest Neighbors (KNN) are performed under three training procedures named general training, distillation training and autoencoder training to optimize and improve the model accuracy and inference performance. Our deep learning-based model can detect malarial parasites from microscopic images with an accuracy of 99.23% while requiring just over 4600 floating point operations. For practical validation of model efficiency, we have deployed the miniaturized model in different mobile phones and a server-backed web application. Data gathered from these environments show that the model can be used to perform inference under 1 s per sample in both offline (mobile only) and online (web application) mode, thus engendering confidence that such models may be deployed for efficient practical inferential systems.
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spelling pubmed-72779802020-06-12 Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application Fuhad, K. M. Faizullah Tuba, Jannat Ferdousey Sarker, Md. Rabiul Ali Momen, Sifat Mohammed, Nabeel Rahman, Tanzilur Diagnostics (Basel) Article Malaria is a life-threatening disease that is spread by the Plasmodium parasites. It is detected by trained microscopists who analyze microscopic blood smear images. Modern deep learning techniques may be used to do this analysis automatically. The need for the trained personnel can be greatly reduced with the development of an automatic accurate and efficient model. In this article, we propose an entirely automated Convolutional Neural Network (CNN) based model for the diagnosis of malaria from the microscopic blood smear images. A variety of techniques including knowledge distillation, data augmentation, Autoencoder, feature extraction by a CNN model and classified by Support Vector Machine (SVM) or K-Nearest Neighbors (KNN) are performed under three training procedures named general training, distillation training and autoencoder training to optimize and improve the model accuracy and inference performance. Our deep learning-based model can detect malarial parasites from microscopic images with an accuracy of 99.23% while requiring just over 4600 floating point operations. For practical validation of model efficiency, we have deployed the miniaturized model in different mobile phones and a server-backed web application. Data gathered from these environments show that the model can be used to perform inference under 1 s per sample in both offline (mobile only) and online (web application) mode, thus engendering confidence that such models may be deployed for efficient practical inferential systems. MDPI 2020-05-20 /pmc/articles/PMC7277980/ /pubmed/32443868 http://dx.doi.org/10.3390/diagnostics10050329 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fuhad, K. M. Faizullah
Tuba, Jannat Ferdousey
Sarker, Md. Rabiul Ali
Momen, Sifat
Mohammed, Nabeel
Rahman, Tanzilur
Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title_full Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title_fullStr Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title_full_unstemmed Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title_short Deep Learning Based Automatic Malaria Parasite Detection from Blood Smear and Its Smartphone Based Application
title_sort deep learning based automatic malaria parasite detection from blood smear and its smartphone based application
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277980/
https://www.ncbi.nlm.nih.gov/pubmed/32443868
http://dx.doi.org/10.3390/diagnostics10050329
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