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Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up

Acute macular neuroretinopathy (AMN) is a rare disorder. We report a case of bilateral AMN in a young female patient, without any risk factors. She referred a positive scotoma in both eyes after flu-like symptoms. Fundus examination revealed parafoveal dark-reddish oval lesions in both eyes. Therefo...

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Autores principales: Porta, Alessandro, Tripodi, Sarah, Toro, Mario Damiano, Rejdak, Robert, Rejdak, Konrad, Zanzottera, Emma Clara, Ferentini, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278004/
https://www.ncbi.nlm.nih.gov/pubmed/32354001
http://dx.doi.org/10.3390/diagnostics10050259
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author Porta, Alessandro
Tripodi, Sarah
Toro, Mario Damiano
Rejdak, Robert
Rejdak, Konrad
Zanzottera, Emma Clara
Ferentini, Fabio
author_facet Porta, Alessandro
Tripodi, Sarah
Toro, Mario Damiano
Rejdak, Robert
Rejdak, Konrad
Zanzottera, Emma Clara
Ferentini, Fabio
author_sort Porta, Alessandro
collection PubMed
description Acute macular neuroretinopathy (AMN) is a rare disorder. We report a case of bilateral AMN in a young female patient, without any risk factors. She referred a positive scotoma in both eyes after flu-like symptoms. Fundus examination revealed parafoveal dark-reddish oval lesions in both eyes. Therefore, we performed visual field, optical coherence tomography (OCT), fluorescein angiography (FA) and indocyanine green angiography (ICG) at baseline and several times during the two years of follow-up. The infrared (IR) imaging showed one rounded hyporeflective lesion in the left eye and two similar lesions in the right eye. The OCT demonstrated the characteristic alterations in the outer retina. The visual field also demonstrated scotomas corresponding with these lesions. The OCT and IR features disappeared at the end of the follow-up except for the left eye, which continued to have hyperreflective spots in the outer plexiform layer. The patient complained about a residual scotoma only in the left eye after two years. Our case shows a difference in disease progression in the two eyes of the same patient, suggesting that several mechanisms can be implicated in the pathology of AMN.
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spelling pubmed-72780042020-06-12 Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up Porta, Alessandro Tripodi, Sarah Toro, Mario Damiano Rejdak, Robert Rejdak, Konrad Zanzottera, Emma Clara Ferentini, Fabio Diagnostics (Basel) Case Report Acute macular neuroretinopathy (AMN) is a rare disorder. We report a case of bilateral AMN in a young female patient, without any risk factors. She referred a positive scotoma in both eyes after flu-like symptoms. Fundus examination revealed parafoveal dark-reddish oval lesions in both eyes. Therefore, we performed visual field, optical coherence tomography (OCT), fluorescein angiography (FA) and indocyanine green angiography (ICG) at baseline and several times during the two years of follow-up. The infrared (IR) imaging showed one rounded hyporeflective lesion in the left eye and two similar lesions in the right eye. The OCT demonstrated the characteristic alterations in the outer retina. The visual field also demonstrated scotomas corresponding with these lesions. The OCT and IR features disappeared at the end of the follow-up except for the left eye, which continued to have hyperreflective spots in the outer plexiform layer. The patient complained about a residual scotoma only in the left eye after two years. Our case shows a difference in disease progression in the two eyes of the same patient, suggesting that several mechanisms can be implicated in the pathology of AMN. MDPI 2020-04-28 /pmc/articles/PMC7278004/ /pubmed/32354001 http://dx.doi.org/10.3390/diagnostics10050259 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Porta, Alessandro
Tripodi, Sarah
Toro, Mario Damiano
Rejdak, Robert
Rejdak, Konrad
Zanzottera, Emma Clara
Ferentini, Fabio
Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title_full Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title_fullStr Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title_full_unstemmed Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title_short Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up
title_sort bilateral acute macular neuroretinopathy in a young patient: imaging and visual field during two-year-follow-up
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278004/
https://www.ncbi.nlm.nih.gov/pubmed/32354001
http://dx.doi.org/10.3390/diagnostics10050259
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