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Site-Specific Antibody–Drug Conjugates in Triple Variable Domain Fab Format

The interest in replacing the conventional immunoglobulin G (IgG) format of monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs) with alternative antibody and antibody-like scaffolds reflects a need to expand their therapeutic utility and potency while retaining their exquisite specifici...

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Detalles Bibliográficos
Autores principales: Hwang, Dobeen, Rader, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278019/
https://www.ncbi.nlm.nih.gov/pubmed/32422893
http://dx.doi.org/10.3390/biom10050764