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Site-Specific Antibody–Drug Conjugates in Triple Variable Domain Fab Format
The interest in replacing the conventional immunoglobulin G (IgG) format of monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs) with alternative antibody and antibody-like scaffolds reflects a need to expand their therapeutic utility and potency while retaining their exquisite specifici...
Autores principales: | Hwang, Dobeen, Rader, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278019/ https://www.ncbi.nlm.nih.gov/pubmed/32422893 http://dx.doi.org/10.3390/biom10050764 |
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