CB2 improves power of cell detection in droplet-based single-cell RNA sequencing data

An important challenge in pre-processing data from droplet-based single-cell RNA sequencing protocols is distinguishing barcodes associated with real cells from those binding background reads. Existing methods test barcodes individually and consequently do not leverage the strong cell-to-cell correl...

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Detalles Bibliográficos
Autores principales: Ni, Zijian, Chen, Shuyang, Brown, Jared, Kendziorski, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278076/
https://www.ncbi.nlm.nih.gov/pubmed/32513247
http://dx.doi.org/10.1186/s13059-020-02054-8

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