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Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis
BACKGROUND: Myocardial infarction (MI) is a major cause of death worldwide. Although percutaneous coronary intervention and coronary artery bypass grafting can prolong life, cardiac damage persists. In particular, cardiomyocytes have no regenerative capacity. Mesenchymal stem cells (MSCs) are attrac...
Autores principales: | Cheng, Hao, Chang, Shufu, Xu, Rende, Chen, Lu, Song, Xiaoyue, Wu, Jian, Qian, Juying, Zou, Yunzeng, Ma, Jianying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278138/ https://www.ncbi.nlm.nih.gov/pubmed/32513270 http://dx.doi.org/10.1186/s13287-020-01737-0 |
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