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Hypoxia-challenged MSC-derived exosomes deliver miR-210 to attenuate post-infarction cardiac apoptosis

BACKGROUND: Myocardial infarction (MI) is a major cause of death worldwide. Although percutaneous coronary intervention and coronary artery bypass grafting can prolong life, cardiac damage persists. In particular, cardiomyocytes have no regenerative capacity. Mesenchymal stem cells (MSCs) are attrac...

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Detalles Bibliográficos
Autores principales: Cheng, Hao, Chang, Shufu, Xu, Rende, Chen, Lu, Song, Xiaoyue, Wu, Jian, Qian, Juying, Zou, Yunzeng, Ma, Jianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278138/
https://www.ncbi.nlm.nih.gov/pubmed/32513270
http://dx.doi.org/10.1186/s13287-020-01737-0

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