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VHL mutation-mediated SALL4 overexpression promotes tumorigenesis and vascularization of clear cell renal cell carcinoma via Akt/GSK-3β signaling

BACKGROUND: Although ongoing development of therapeutic strategies contributes to the improvements in clinical management, clear cell renal cell carcinoma (ccRCC) deaths originate mainly from radiochemoresistant and metastatic disease. Transcription factor SALL4 has been implicated in tumorigenesis...

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Detalles Bibliográficos
Autores principales:	Sun, Jinbo, Tang, Qisheng, Gao, Yongheng, Zhang, Wei, Zhao, Zhining, Yang, Fan, Hu, Xiangnan, Zhang, Dan, Wang, Yong, Zhang, Huizhong, Song, Bin, Zhang, Bo, Wang, He
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278163/ https://www.ncbi.nlm.nih.gov/pubmed/32513235 http://dx.doi.org/10.1186/s13046-020-01609-8

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