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Exposure of Intestinal Epithelial Cells to 2′-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development
Intestinal epithelial cells (IEC) release immunomodulatory galectins upon exposure to CpG DNA (mimicking bacterial triggers) and short-chain galacto- and long-chain fructo-oligosaccharides (GF). This study aims to investigate the immunomodulatory properties of 2′-fucosyllactose (2′-FL), a non-digest...
Autores principales: | Ayechu-Muruzabal, Veronica, Overbeek, Saskia A., Kostadinova, Atanaska I., Stahl, Bernd, Garssen, Johan, van’t Land, Belinda, Willemsen, Linette E.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278199/ https://www.ncbi.nlm.nih.gov/pubmed/32438601 http://dx.doi.org/10.3390/biom10050784 |
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