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The Absence of Serotonin in the Brain Alters Acute Stress Responsiveness by Interfering With the Genomic Function of the Glucocorticoid Receptors
Alterations in serotonergic transmission have been related to a major predisposition to develop psychiatric pathologies, such as depression. We took advantage of tryptophan hydroxylase (TPH) 2 deficient rats, characterized by a complete absence of serotonin in the brain, to evaluate whether a vulner...
Autores principales: | Sbrini, Giulia, Brivio, Paola, Peeva, Polina Mineva, Todiras, Mihail, Bader, Michael, Alenina, Natalia, Calabrese, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278285/ https://www.ncbi.nlm.nih.gov/pubmed/32547368 http://dx.doi.org/10.3389/fncel.2020.00128 |
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