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Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

The microtubule-associated protein Tau is implicated in the pathogenesis of several neurodegenerative disorders, including Alzheimer's disease. Increasing evidence suggests that post-translational modifications play critical roles in regulating Tau's normal functions and its pathogenic pro...

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Detalles Bibliográficos
Autores principales:	Ait-Bouziad, Nadine, Chiki, Anass, Limorenko, Galina, Xiao, Shifeng, Eliezer, David, Lashuel, Hilal A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278352/ https://www.ncbi.nlm.nih.gov/pubmed/32341125 http://dx.doi.org/10.1074/jbc.RA119.012517

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