The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium

SIMPLE SUMMARY: The protease elastase found in neutrophil extracellular traps appears to be associated with equine endometrial fibrosis by its stimulatory effect on extracellular matrix (ECM) components, leading to an increase in collagen relative abundance. Metallopeptidases (MMP-2 and -9) are enzy...

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Detalles Bibliográficos
Autores principales: Amaral, Ana, Fernandes, Carina, Rebordão, Maria Rosa, Szóstek-Mioduchowska, Anna, Lukasik, Karolina, Gawronska-Kozak, Barbara, Telo da Gama, Luís, Skarzynski, Dariusz J., Ferreira-Dias, Graça
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://www.ncbi.nlm.nih.gov/pubmed/32429399
http://dx.doi.org/10.3390/ani10050863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://www.ncbi.nlm.nih.gov/pubmed/32429399
http://dx.doi.org/10.3390/ani10050863

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