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HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP‐43 proteinopathies

TAR DNA‐binding protein 43 (TDP‐43) has been implicated in frontotemporal lobar degeneration with ubiquitin‐positive inclusions (FTLD‐TDP) and amyotrophic lateral sclerosis. Histone deacetylase 1 (HDAC1) is involved in DNA repair and neuroprotection in numerous neurodegenerative diseases. However, t...

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Detalles Bibliográficos
Autores principales:	Wu, Cheng‐Chun, Jin, Lee‐Way, Wang, I‐Fang, Wei, Wei‐Yen, Ho, Pei‐Chuan, Liu, Yu‐Chih, Tsai, Kuen‐Jer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278561/ https://www.ncbi.nlm.nih.gov/pubmed/32449313 http://dx.doi.org/10.15252/emmm.201910622

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