Cargando…

Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity

This study aimed to investigate the metabolic effect of yogurt fermented by Lactobacillus fermentum TSI and S2 isolated from a Mongolian traditional dairy product on rats with high-fat-diet-induced obesity. Quality characteristics of yogurt fermented by commercial starter (CON), L. fermentum TSI2 (T...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Won-Young, Hong, Go-Eun, Lee, Ha-Jung, Yeon, Su-Jung, Paik, Hyun-Dong, Hosaka, Yoshinao Z., Lee, Chi-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278578/
https://www.ncbi.nlm.nih.gov/pubmed/32384659
http://dx.doi.org/10.3390/foods9050594
_version_ 1783543363313598464
author Cho, Won-Young
Hong, Go-Eun
Lee, Ha-Jung
Yeon, Su-Jung
Paik, Hyun-Dong
Hosaka, Yoshinao Z.
Lee, Chi-Ho
author_facet Cho, Won-Young
Hong, Go-Eun
Lee, Ha-Jung
Yeon, Su-Jung
Paik, Hyun-Dong
Hosaka, Yoshinao Z.
Lee, Chi-Ho
author_sort Cho, Won-Young
collection PubMed
description This study aimed to investigate the metabolic effect of yogurt fermented by Lactobacillus fermentum TSI and S2 isolated from a Mongolian traditional dairy product on rats with high-fat-diet-induced obesity. Quality characteristics of yogurt fermented by commercial starter (CON), L. fermentum TSI2 (TSI2 group), L. fermentum S2 (S2 group), and mixed TSI2 and S2 strains at 1:1 (MIX group), were verified. Six-week-old male Sprague-Dawley rats were divided into five groups and administered the following diets: group NOR, normal diet with oral saline administration; group HF, high-fat diet (HD) with oral saline administration; group TSI, HD and L. fermentum TSI-fermented yogurt; group S2, HD and L. fermentum S2-fermented yogurt; and group MIX, HD and MIX-fermented yogurt. After eight weeks, the HD groups displayed significantly increased body weight and fat, serum cholesterol, and abdominal adipose tissue levels. However, serum HDL cholesterol levels were higher, triglyceride levels were lower, and abdominal adipocytes were smaller in the TSI and S2 groups than in the HF group. These results indicate that L. fermentum TSI reduces abdominal fat and improves blood lipid metabolism in HD-induced obese rats.
format Online
Article
Text
id pubmed-7278578
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72785782020-06-12 Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity Cho, Won-Young Hong, Go-Eun Lee, Ha-Jung Yeon, Su-Jung Paik, Hyun-Dong Hosaka, Yoshinao Z. Lee, Chi-Ho Foods Article This study aimed to investigate the metabolic effect of yogurt fermented by Lactobacillus fermentum TSI and S2 isolated from a Mongolian traditional dairy product on rats with high-fat-diet-induced obesity. Quality characteristics of yogurt fermented by commercial starter (CON), L. fermentum TSI2 (TSI2 group), L. fermentum S2 (S2 group), and mixed TSI2 and S2 strains at 1:1 (MIX group), were verified. Six-week-old male Sprague-Dawley rats were divided into five groups and administered the following diets: group NOR, normal diet with oral saline administration; group HF, high-fat diet (HD) with oral saline administration; group TSI, HD and L. fermentum TSI-fermented yogurt; group S2, HD and L. fermentum S2-fermented yogurt; and group MIX, HD and MIX-fermented yogurt. After eight weeks, the HD groups displayed significantly increased body weight and fat, serum cholesterol, and abdominal adipose tissue levels. However, serum HDL cholesterol levels were higher, triglyceride levels were lower, and abdominal adipocytes were smaller in the TSI and S2 groups than in the HF group. These results indicate that L. fermentum TSI reduces abdominal fat and improves blood lipid metabolism in HD-induced obese rats. MDPI 2020-05-06 /pmc/articles/PMC7278578/ /pubmed/32384659 http://dx.doi.org/10.3390/foods9050594 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cho, Won-Young
Hong, Go-Eun
Lee, Ha-Jung
Yeon, Su-Jung
Paik, Hyun-Dong
Hosaka, Yoshinao Z.
Lee, Chi-Ho
Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title_full Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title_fullStr Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title_full_unstemmed Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title_short Effect of Yogurt Fermented by Lactobacillus Fermentum TSI and L. Fermentum S2 Derived from a Mongolian Traditional Dairy Product on Rats with High-Fat-Diet-Induced Obesity
title_sort effect of yogurt fermented by lactobacillus fermentum tsi and l. fermentum s2 derived from a mongolian traditional dairy product on rats with high-fat-diet-induced obesity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278578/
https://www.ncbi.nlm.nih.gov/pubmed/32384659
http://dx.doi.org/10.3390/foods9050594
work_keys_str_mv AT chowonyoung effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT honggoeun effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT leehajung effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT yeonsujung effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT paikhyundong effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT hosakayoshinaoz effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity
AT leechiho effectofyogurtfermentedbylactobacillusfermentumtsiandlfermentums2derivedfromamongoliantraditionaldairyproductonratswithhighfatdietinducedobesity