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An effective inactivant based on singlet oxygen-mediated lipid oxidation implicates a new paradigm for broad-spectrum antivirals
Emerging viral pathogens cause substantial morbidity and pose a severe threat to health worldwide. However, a universal antiviral strategy for producing safe and immunogenic inactivated vaccines is lacking. Here, we report an antiviral strategy using the novel singlet oxygen ((1)O(2))-generating age...
Autores principales: | Zeng, Lei, Wang, Meng-Di, Ming, Sheng-Li, Li, Guo-Li, Yu, Peng-Wei, Qi, Yan-Li, Jiang, Da-Wei, Yang, Guo-Yu, Wang, Jiang, Chu, Bei-Bei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278711/ https://www.ncbi.nlm.nih.gov/pubmed/32535542 http://dx.doi.org/10.1016/j.redox.2020.101601 |
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