Higher Blood Uric Acid in Female Humans and Mice as a Protective Factor against Pathophysiological Decline of Lung Function

The oxidant/antioxidant imbalance plays a pivotal role in the lung. Uric acid (UA), an endogenous antioxidant, is highly present in lung tissue, however, its impact on lung function under pathophysiological conditions remains unknown. In this work, pharmacological and genetic inhibition of UA metabo...

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Detalles Bibliográficos
Autores principales: Fujikawa, Haruka, Sakamoto, Yuki, Masuda, Natsuki, Oniki, Kentaro, Kamei, Shunsuke, Nohara, Hirofumi, Nakashima, Ryunosuke, Maruta, Kasumi, Kawakami, Taisei, Eto, Yuka, Takahashi, Noriki, Takeo, Toru, Nakagata, Naomi, Watanabe, Hiroshi, Otake, Koji, Ogata, Yasuhiro, Tomioka, Naoko H., Hosoyamada, Makoto, Takada, Tappei, Ueno-Shuto, Keiko, Suico, Mary Ann, Kai, Hirofumi, Saruwatari, Junji, Shuto, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278835/
https://www.ncbi.nlm.nih.gov/pubmed/32384764
http://dx.doi.org/10.3390/antiox9050387

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