Cargando…

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases

The intestinal epithelial apical junctional complex, which includes tight and adherens junctions, contributes to the intestinal barrier function via their role in regulating paracellular permeability. Myosin light chain II (MLC-2), has been shown to be a critical regulatory protein in altering parac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Younggeon, Blikslager, Anthony T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278945/ https://www.ncbi.nlm.nih.gov/pubmed/32443411 http://dx.doi.org/10.3390/ijms21103550

Ejemplares similares

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
por: Kaneko-Kawano, Takako, et al.
Publicado: (2012)

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
por: Lou, Sunny S., et al.
Publicado: (2015)

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis
por: He, Wei-Qi, et al.
Publicado: (2020)

Myosin Light Chain Kinase Mediates Intestinal Barrier Disruption following Burn Injury
por: Chen, Chuanli, et al.
Publicado: (2012)

Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
por: Murray, Ailish, et al.
Publicado: (2010)

Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function
por: Dudek, Steven M., et al.
Publicado: (2010)

Rho-associated kinase and zipper-interacting protein kinase, but not myosin light chain kinase, are involved in the regulation of myosin phosphorylation in serum-stimulated human arterial smooth muscle cells
por: Deng, Jing-Ti, et al.
Publicado: (2019)

Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle
por: Kirschstein, Timo, et al.
Publicado: (2015)

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway
por: Lv, Yanni, et al.
Publicado: (2020)

Rho Kinase's Role in Myosin Recruitment to the Equatorial Cortex of Mitotic Drosophila S2 Cells Is for Myosin Regulatory Light Chain Phosphorylation
por: Dean, Sara O., et al.
Publicado: (2006)

Role of myosin light chain kinase in intestinal epithelial barrier defects in a rat model of bowel obstruction
por: Wu, Chi-Chin, et al.
Publicado: (2010)

The sphingosine-1-phosphate/RhoA/Rho associated kinases/myosin light chain pathway in detrusor of female rats is down-regulated in response to ovariectomy
por: Zhang, Wei, et al.
Publicado: (2020)

Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells
por: Aguilar, Hector N, et al.
Publicado: (2012)

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function
Publicado: (1987)

MiR-31 Regulates Rho-Associated Kinase-Myosin Light Chain (ROCK-MLC) Pathway and Inhibits Gastric Cancer Invasion: Roles of RhoA
por: Chen, Zhuo, et al.
Publicado: (2016)

Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs
por: Sharanek, Ahmad, et al.
Publicado: (2016)

Activation of G(12)/G(13) Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets
por: Klages, Birgit, et al.
Publicado: (1999)

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation
por: Gilbert, Shila, et al.
Publicado: (2012)

Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
por: Reddi, Benjamin AJ, et al.
Publicado: (2015)

Phosphorylation of Myosin-Binding Subunit (Mbs) of Myosin Phosphatase by Rho-Kinase in Vivo
por: Kawano, Yoji, et al.
Publicado: (1999)

Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis
por: Taneja, Nilay, et al.
Publicado: (2021)

TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase‐dependent mechanism
por: Xu, Chang, et al.
Publicado: (2015)

NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
por: Müller, Marion, et al.
Publicado: (2022)

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
por: Hitsumoto, Tatsuro, et al.
Publicado: (2023)

The Rho kinases I and II regulate different aspects of myosin II activity
por: Yoneda, Atsuko, et al.
Publicado: (2005)

Association of myosin light chain kinase with lymphocyte membrane- cytoskeleton complex
Publicado: (1982)

The Effect of Myosin Light Chain Kinase on the Occurrence and Development of Intracranial Aneurysm
por: Song, Yaying, et al.
Publicado: (2018)

Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase
por: Fukata, Yuko, et al.
Publicado: (1998)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development
por: Verdier, Valerie, et al.
Publicado: (2006)

Brain-derived neurotrophic factor regulates LYN kinase–mediated myosin light chain kinase activation to modulate nonmuscle myosin II activity in hippocampal neurons
por: Li, Xiaobing, et al.
Publicado: (2022)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase
Publicado: (1988)

Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation
Publicado: (1995)

Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment
por: Cao, Feng, et al.
Publicado: (2020)

Effects of phosphorylation by myosin light chain kinase on the structure of Limulus thick filaments
Publicado: (1991)

Localization and Activity of Myosin Light Chain Kinase Isoforms during the Cell Cycle
por: Poperechnaya, Angela, et al.
Publicado: (2000)

The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts
por: Chang, Audrey N., et al.
Publicado: (2013)

Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase
por: Islam, Yasmin F. K., et al.
Publicado: (2016)

Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory Diseases
por: Xiong, Yongjian, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_akbnunlk5hh4ega5mkto1kto4d