Reduction of Secreted Frizzled-Related Protein 5 Drives Vascular Calcification through Wnt3a-Mediated Rho/ROCK/JNK Signaling in Chronic Kidney Disease

Vascular calcification (VC) is commonly associated with bone loss in patients with chronic kidney disease (CKD). The Wingless-related integration site (Wnt) regulates osteoblast activation through canonical signaling pathways, but the common pathophysiology of these pathways during VC and bone loss...

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Detalles Bibliográficos
Autores principales: Oh, Yun Jung, Kim, Hyunsook, Kim, Ae Jin, Ro, Han, Chang, Jae Hyun, Lee, Hyun Hee, Chung, Wookyung, Jun, Hee-Sook, Jung, Ji Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278993/
https://www.ncbi.nlm.nih.gov/pubmed/32429518
http://dx.doi.org/10.3390/ijms21103539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278993/
https://www.ncbi.nlm.nih.gov/pubmed/32429518
http://dx.doi.org/10.3390/ijms21103539

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