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CX3CR1-Targeted PLGA Nanoparticles Reduce Microglia Activation and Pain Behavior in Rats with Spinal Nerve Ligation

Activation of CX3CR1 in microglia plays an important role in the development of neuropathic pain. Here, we investigated whether neuropathic pain could be attenuated in spinal nerve ligation (SNL)-induced rats by reducing microglial activation through the use of poly(D,L-lactic-co-glycolic acid) (PLG...

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Detalles Bibliográficos
Autores principales:	Noh, Chan, Shin, Hyo Jung, Lee, Seounghun, Kim, Song I, Kim, Yoon-Hee, Lee, Won Hyung, Kim, Dong Woon, Lee, Sun Yeul, Ko, Young Kwon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279022/ https://www.ncbi.nlm.nih.gov/pubmed/32423102 http://dx.doi.org/10.3390/ijms21103469

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