Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials

This analysis includes pooled data from 2 placebo-controlled maternal influenza immunization trials, with a separate analysis on a meningococcal conjugate vaccine-controlled maternal influenza immunization trial. Maternal influenza immunization was not associated with infant or maternal all-cause mo...

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Autores principales: Clark, Dayna R., Omer, Saad B., Tapia, Milagritos D., Nunes, Marta C., Cutland, Clare L., Tielsch, James M., Wairagkar, Niteen, Madhi, Shabir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Williams & Wilkins 2020
Materias:
Maternal-Neonatal Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279057/
https://www.ncbi.nlm.nih.gov/pubmed/32379201
http://dx.doi.org/10.1097/INF.0000000000002629
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author Clark, Dayna R.
Omer, Saad B.
Tapia, Milagritos D.
Nunes, Marta C.
Cutland, Clare L.
Tielsch, James M.
Wairagkar, Niteen
Madhi, Shabir A.
author_facet Clark, Dayna R.
Omer, Saad B.
Tapia, Milagritos D.
Nunes, Marta C.
Cutland, Clare L.
Tielsch, James M.
Wairagkar, Niteen
Madhi, Shabir A.
author_sort Clark, Dayna R.
collection PubMed
description This analysis includes pooled data from 2 placebo-controlled maternal influenza immunization trials, with a separate analysis on a meningococcal conjugate vaccine-controlled maternal influenza immunization trial. Maternal influenza immunization was not associated with infant or maternal all-cause mortality in placebo-controlled trials. In the meningococcal conjugate vaccine-controlled trial, there were fewer deaths during low or any influenza circulation weeks among infants whose mothers received meningococcal conjugate vaccine. ClinicalTrials.gov identifiers: NCT01430689, NCT01034254 and NCT02465190.
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spelling pubmed-72790572020-06-29 Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials Clark, Dayna R. Omer, Saad B. Tapia, Milagritos D. Nunes, Marta C. Cutland, Clare L. Tielsch, James M. Wairagkar, Niteen Madhi, Shabir A. Pediatr Infect Dis J Maternal-Neonatal Reports This analysis includes pooled data from 2 placebo-controlled maternal influenza immunization trials, with a separate analysis on a meningococcal conjugate vaccine-controlled maternal influenza immunization trial. Maternal influenza immunization was not associated with infant or maternal all-cause mortality in placebo-controlled trials. In the meningococcal conjugate vaccine-controlled trial, there were fewer deaths during low or any influenza circulation weeks among infants whose mothers received meningococcal conjugate vaccine. ClinicalTrials.gov identifiers: NCT01430689, NCT01034254 and NCT02465190. Williams & Wilkins 2020-07 2020-04-16 /pmc/articles/PMC7279057/ /pubmed/32379201 http://dx.doi.org/10.1097/INF.0000000000002629 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Maternal-Neonatal Reports
Clark, Dayna R.
Omer, Saad B.
Tapia, Milagritos D.
Nunes, Marta C.
Cutland, Clare L.
Tielsch, James M.
Wairagkar, Niteen
Madhi, Shabir A.
Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title_full Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title_fullStr Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title_full_unstemmed Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title_short Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials
title_sort influenza or meningococcal immunization during pregnancy and mortality in women and infants: a pooled analysis of randomized controlled trials
topic Maternal-Neonatal Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279057/
https://www.ncbi.nlm.nih.gov/pubmed/32379201
http://dx.doi.org/10.1097/INF.0000000000002629
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