FLCN-regulated miRNAs suppressed reparative response in cells and pulmonary lesions of Birt-Hogg-Dubé syndrome

BACKGROUND: Birt-Hogg-Dubé Syndrome (BHDS) characterised by skin fibrofolliculomas, kidney tumour and pulmonary cysts/pneumothorax is caused by folliculin (FLCN) germline mutations. The pathology of both neoplasia and focused tissue loss of BHDS strongly features tissue-specific behaviour of the gen...

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Detalles Bibliográficos
Autores principales: Min, Haiyan, Ma, Dehua, Zou, Wei, Wu, Yongzheng, Ding, Yibing, Zhu, Chengchu, Lin, Anqi, Song, Shiyu, Liang, Qiao, Chen, Baofu, Zhang, Bin, Wan, Yueming, Ye, Minhua, Pan, Yanqing, Wen, Yanting, Yi, long, Gao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Orphan Lung Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279199/
https://www.ncbi.nlm.nih.gov/pubmed/32184379
http://dx.doi.org/10.1136/thoraxjnl-2019-213225

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