TP53 in Myelodysplastic Syndromes: Recent Biological and Clinical Findings

TP53 dysregulation plays a pivotal role in the molecular pathogenesis of myelodysplastic syndromes (MDS), identifying a subgroup of patients with peculiar features. In this review we report the recent biological and clinical findings of TP53-mutated MDS, focusing on the molecular pathways activation...

Descripción completa

Detalles Bibliográficos
Autores principales: Cumbo, Cosimo, Tota, Giuseppina, Anelli, Luisa, Zagaria, Antonella, Specchia, Giorgina, Albano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279310/
https://www.ncbi.nlm.nih.gov/pubmed/32414002
http://dx.doi.org/10.3390/ijms21103432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279310/
https://www.ncbi.nlm.nih.gov/pubmed/32414002
http://dx.doi.org/10.3390/ijms21103432

Ejemplares similares