Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer

The overexpression of PRMT5 is highly correlated to poor clinical outcomes for colorectal cancer (CRC) patients. Importantly, our previous work demonstrated that PRMT5 overexpression could substantially augment activation of the nuclear factor kappa B (NF-κB) via methylation of arginine 30 (R30) on...

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Detalles Bibliográficos
Autores principales: Hartley, Antja-Voy, Wang, Benlian, Jiang, Guanglong, Wei, Han, Sun, Mengyao, Prabhu, Lakshmi, Martin, Matthew, Safa, Ahmad, Sun, Steven, Liu, Yunlong, Lu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279388/
https://www.ncbi.nlm.nih.gov/pubmed/32456215
http://dx.doi.org/10.3390/ijms21103684

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