Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis

Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells. Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular Pattern which can promote inflammation during tissue injury. However, the role of CypA in kidney disease is largely unknow...

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Detalles Bibliográficos
Autores principales: Leong, Khai Gene, Ozols, Elyce, Kanellis, John, Nikolic-Paterson, David J., Ma, Frank Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279441/
https://www.ncbi.nlm.nih.gov/pubmed/32455976
http://dx.doi.org/10.3390/ijms21103667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279441/
https://www.ncbi.nlm.nih.gov/pubmed/32455976
http://dx.doi.org/10.3390/ijms21103667

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