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Cyclophilin A Promotes Inflammation in Acute Kidney Injury but Not in Renal Fibrosis
Cyclophilin A (CypA) is a highly abundant protein in the cytoplasm of most mammalian cells. Beyond its homeostatic role in protein folding, CypA is a Damage-Associated Molecular Pattern which can promote inflammation during tissue injury. However, the role of CypA in kidney disease is largely unknow...
Autores principales: | Leong, Khai Gene, Ozols, Elyce, Kanellis, John, Nikolic-Paterson, David J., Ma, Frank Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279441/ https://www.ncbi.nlm.nih.gov/pubmed/32455976 http://dx.doi.org/10.3390/ijms21103667 |
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