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ASC-Exosomes Ameliorate the Disease Progression in SOD1(G93A) Murine Model Underlining Their Potential Therapeutic Use in Human ALS

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive degeneration of motoneurons. To date, there is no effective treatment available. Exosomes are extracellular vesicles that play important roles in intercellular communication, recapitulating the effe...

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Detalles Bibliográficos
Autores principales: Bonafede, Roberta, Turano, Ermanna, Scambi, Ilaria, Busato, Alice, Bontempi, Pietro, Virla, Federica, Schiaffino, Lorenzo, Marzola, Pasquina, Bonetti, Bruno, Mariotti, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279464/
https://www.ncbi.nlm.nih.gov/pubmed/32455791
http://dx.doi.org/10.3390/ijms21103651