Dual Target Ligands with 4-tert-Butylphenoxy Scaffold as Histamine H(3) Receptor Antagonists and Monoamine Oxidase B Inhibitors

Dual target ligands are a promising concept for the treatment of Parkinson’s disease (PD). A combination of monoamine oxidase B (MAO B) inhibition with histamine H(3) receptor (H(3)R) antagonism could have positive effects on dopamine regulation. Thus, a series of twenty-seven 4-tert-butylphenoxyalk...

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Detalles Bibliográficos
Autores principales: Łażewska, Dorota, Olejarz-Maciej, Agnieszka, Reiner, David, Kaleta, Maria, Latacz, Gniewomir, Zygmunt, Małgorzata, Doroz-Płonka, Agata, Karcz, Tadeusz, Frank, Annika, Stark, Holger, Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279487/
https://www.ncbi.nlm.nih.gov/pubmed/32408504
http://dx.doi.org/10.3390/ijms21103411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279487/
https://www.ncbi.nlm.nih.gov/pubmed/32408504
http://dx.doi.org/10.3390/ijms21103411

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