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Down-Regulation of miR-23a-3p Mediates Irradiation-Induced Neuronal Apoptosis

Radiation-induced central nervous system toxicity is a significant risk factor for patients receiving cancer radiotherapy. Surprisingly, the mechanisms responsible for the DNA damage-triggered neuronal cell death following irradiation have yet to be deciphered. Using primary cortical neuronal cultur...

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Detalles Bibliográficos
Autores principales: Sabirzhanov, Boris, Makarevich, Oleg, Barrett, James, Jackson, Isabel L., Faden, Alan I., Stoica, Bogdan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279507/
https://www.ncbi.nlm.nih.gov/pubmed/32456284
http://dx.doi.org/10.3390/ijms21103695