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A Precise Nanostructure of Folate-Overhung Mitoxantrone DNA Tetrahedron for Targeted Capture Leukemia

Regular chemotherapy cannot eliminate leukemic cells, due to the sparse distribution of cancer cells in leukemia patients. Here, we report a precise nanostructure of folate-overhung mitoxantrone DNA tetrahedron that enables the treatment of leukemic cells by targeted action. Folate is used as a targ...

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Detalles Bibliográficos
Autores principales: Bu, Ying-Zi, Xu, Jia-Rui, Luo, Qian, Chen, Ming, Mu, Li-Min, Lu, Wan-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279534/
https://www.ncbi.nlm.nih.gov/pubmed/32429472
http://dx.doi.org/10.3390/nano10050951