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Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract
An innovative, biomimetic, green synthesis approach was exploited for the synthesis of humane and environmental friendly nanomaterials for biomedical applications. Ultrafine bonelike apatite (BAp) 2D plate-like structures were prepared using fenugreek seed extract during the biosynthesis wet-chemica...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279542/ https://www.ncbi.nlm.nih.gov/pubmed/32397480 http://dx.doi.org/10.3390/nano10050919 |
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author | Abdal-hay, Abdalla Fouad, H. A. ALshammari, Basheer Khalil, Khalil Abdelrazek |
author_facet | Abdal-hay, Abdalla Fouad, H. A. ALshammari, Basheer Khalil, Khalil Abdelrazek |
author_sort | Abdal-hay, Abdalla |
collection | PubMed |
description | An innovative, biomimetic, green synthesis approach was exploited for the synthesis of humane and environmental friendly nanomaterials for biomedical applications. Ultrafine bonelike apatite (BAp) 2D plate-like structures were prepared using fenugreek seed extract during the biosynthesis wet-chemical precipitation route. The chemical analysis, morphology and structure of the prepared 2D nanoplates were characterized by inductively coupled plasma atomic emission spectroscopy (ICP-OES), electron microscopy (SEM and TEM), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. A 2D plate-like nanostructure of BAp with an average width (length) of 12.67 ± 2 nm and thickness of 3.8 ± 1.2 nm was obtained. BAp 2D crystals were tuned by interaction with the fenugreek organic molecules during the fabrication process. In addition to Ca and P ions, bone mineral sources such as K, Mg, Na, SO(4) and CO(3) ions were incorporated into BAp nanoplates using fenugreek seed extract. The overall organic molecule concentration in the reaction process increased the effectiveness of hydroxyl groups as nucleation sites for BAp crystals. Accordingly, the size of the biosynthesized BAp plate-like structure was reduced to its lowest value. Biosynthesis BAp 2D plate-like nanocrystals showed good viability and higher growth of MC3T3 osteoblast-like structures than that of the control sample. BAp 2D nanoplates prepared by a facile, ecofriendly and cost-effective approach could be considered a favorable osteoconductive inorganic biomaterial for bone regeneration applications. |
format | Online Article Text |
id | pubmed-7279542 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72795422020-06-15 Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract Abdal-hay, Abdalla Fouad, H. A. ALshammari, Basheer Khalil, Khalil Abdelrazek Nanomaterials (Basel) Article An innovative, biomimetic, green synthesis approach was exploited for the synthesis of humane and environmental friendly nanomaterials for biomedical applications. Ultrafine bonelike apatite (BAp) 2D plate-like structures were prepared using fenugreek seed extract during the biosynthesis wet-chemical precipitation route. The chemical analysis, morphology and structure of the prepared 2D nanoplates were characterized by inductively coupled plasma atomic emission spectroscopy (ICP-OES), electron microscopy (SEM and TEM), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy. A 2D plate-like nanostructure of BAp with an average width (length) of 12.67 ± 2 nm and thickness of 3.8 ± 1.2 nm was obtained. BAp 2D crystals were tuned by interaction with the fenugreek organic molecules during the fabrication process. In addition to Ca and P ions, bone mineral sources such as K, Mg, Na, SO(4) and CO(3) ions were incorporated into BAp nanoplates using fenugreek seed extract. The overall organic molecule concentration in the reaction process increased the effectiveness of hydroxyl groups as nucleation sites for BAp crystals. Accordingly, the size of the biosynthesized BAp plate-like structure was reduced to its lowest value. Biosynthesis BAp 2D plate-like nanocrystals showed good viability and higher growth of MC3T3 osteoblast-like structures than that of the control sample. BAp 2D nanoplates prepared by a facile, ecofriendly and cost-effective approach could be considered a favorable osteoconductive inorganic biomaterial for bone regeneration applications. MDPI 2020-05-09 /pmc/articles/PMC7279542/ /pubmed/32397480 http://dx.doi.org/10.3390/nano10050919 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Abdal-hay, Abdalla Fouad, H. A. ALshammari, Basheer Khalil, Khalil Abdelrazek Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title | Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title_full | Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title_fullStr | Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title_full_unstemmed | Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title_short | Biosynthesis of Bonelike Apatite 2D Nanoplate Structures Using Fenugreek Seed Extract |
title_sort | biosynthesis of bonelike apatite 2d nanoplate structures using fenugreek seed extract |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279542/ https://www.ncbi.nlm.nih.gov/pubmed/32397480 http://dx.doi.org/10.3390/nano10050919 |
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