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Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticle...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279544/ https://www.ncbi.nlm.nih.gov/pubmed/32455981 http://dx.doi.org/10.3390/nano10050997 |
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author | Saratale, Ganesh Dattatraya Saratale, Rijuta Ganesh Ghodake, Gajanan Shinde, Surendra Kim, Dae-Young Alyousef, Abdullah A. Arshad, Mohammed Syed, Asad Pant, Deepak Shin, Han-Seung |
author_facet | Saratale, Ganesh Dattatraya Saratale, Rijuta Ganesh Ghodake, Gajanan Shinde, Surendra Kim, Dae-Young Alyousef, Abdullah A. Arshad, Mohammed Syed, Asad Pant, Deepak Shin, Han-Seung |
author_sort | Saratale, Ganesh Dattatraya |
collection | PubMed |
description | Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticles (AgNPs–CTC) as the sensing element. Almost all of the tested aminoglycoside antibiotics can rapidly induce the aggregation of AgNPs, along with a color change from yellow to orange/red. The selective detection of aminoglycoside antibiotics, including tobramycin, streptomycin, amikacin, gentamicin, neomycin, and kanamycin, with other types of antibiotics, can be achieved by ultraviolet (UV) spectroscopy. This developed colorimetric assay has ability to detect various AMGs using in-depth surface plasmon resonance (SPR) studies. With this determination of streptomycin and kanamycin was achieved at the picomolar level (pM) by using a UV–visible spectrophotometer. Under aqueous conditions, the linear range of the colorimetric sensor for streptomycin and kanamycin was 1000–1,1000 and 120–480 pM, respectively. The corresponding limit of detection was 2000 pM and 120 pM, respectively. Thus, the validated dual colorimetric and ratiometric method can find various analytical applications for the ultrasensitive and rapid detection of AMG antibiotics in water samples. |
format | Online Article Text |
id | pubmed-7279544 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72795442020-06-15 Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin Saratale, Ganesh Dattatraya Saratale, Rijuta Ganesh Ghodake, Gajanan Shinde, Surendra Kim, Dae-Young Alyousef, Abdullah A. Arshad, Mohammed Syed, Asad Pant, Deepak Shin, Han-Seung Nanomaterials (Basel) Article Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticles (AgNPs–CTC) as the sensing element. Almost all of the tested aminoglycoside antibiotics can rapidly induce the aggregation of AgNPs, along with a color change from yellow to orange/red. The selective detection of aminoglycoside antibiotics, including tobramycin, streptomycin, amikacin, gentamicin, neomycin, and kanamycin, with other types of antibiotics, can be achieved by ultraviolet (UV) spectroscopy. This developed colorimetric assay has ability to detect various AMGs using in-depth surface plasmon resonance (SPR) studies. With this determination of streptomycin and kanamycin was achieved at the picomolar level (pM) by using a UV–visible spectrophotometer. Under aqueous conditions, the linear range of the colorimetric sensor for streptomycin and kanamycin was 1000–1,1000 and 120–480 pM, respectively. The corresponding limit of detection was 2000 pM and 120 pM, respectively. Thus, the validated dual colorimetric and ratiometric method can find various analytical applications for the ultrasensitive and rapid detection of AMG antibiotics in water samples. MDPI 2020-05-22 /pmc/articles/PMC7279544/ /pubmed/32455981 http://dx.doi.org/10.3390/nano10050997 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saratale, Ganesh Dattatraya Saratale, Rijuta Ganesh Ghodake, Gajanan Shinde, Surendra Kim, Dae-Young Alyousef, Abdullah A. Arshad, Mohammed Syed, Asad Pant, Deepak Shin, Han-Seung Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title | Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title_full | Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title_fullStr | Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title_full_unstemmed | Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title_short | Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin |
title_sort | chlortetracycline-functionalized silver nanoparticles as a colorimetric probe for aminoglycosides: ultrasensitive determination of kanamycin and streptomycin |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279544/ https://www.ncbi.nlm.nih.gov/pubmed/32455981 http://dx.doi.org/10.3390/nano10050997 |
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