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Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin

Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticle...

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Autores principales: Saratale, Ganesh Dattatraya, Saratale, Rijuta Ganesh, Ghodake, Gajanan, Shinde, Surendra, Kim, Dae-Young, Alyousef, Abdullah A., Arshad, Mohammed, Syed, Asad, Pant, Deepak, Shin, Han-Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279544/
https://www.ncbi.nlm.nih.gov/pubmed/32455981
http://dx.doi.org/10.3390/nano10050997
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author Saratale, Ganesh Dattatraya
Saratale, Rijuta Ganesh
Ghodake, Gajanan
Shinde, Surendra
Kim, Dae-Young
Alyousef, Abdullah A.
Arshad, Mohammed
Syed, Asad
Pant, Deepak
Shin, Han-Seung
author_facet Saratale, Ganesh Dattatraya
Saratale, Rijuta Ganesh
Ghodake, Gajanan
Shinde, Surendra
Kim, Dae-Young
Alyousef, Abdullah A.
Arshad, Mohammed
Syed, Asad
Pant, Deepak
Shin, Han-Seung
author_sort Saratale, Ganesh Dattatraya
collection PubMed
description Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticles (AgNPs–CTC) as the sensing element. Almost all of the tested aminoglycoside antibiotics can rapidly induce the aggregation of AgNPs, along with a color change from yellow to orange/red. The selective detection of aminoglycoside antibiotics, including tobramycin, streptomycin, amikacin, gentamicin, neomycin, and kanamycin, with other types of antibiotics, can be achieved by ultraviolet (UV) spectroscopy. This developed colorimetric assay has ability to detect various AMGs using in-depth surface plasmon resonance (SPR) studies. With this determination of streptomycin and kanamycin was achieved at the picomolar level (pM) by using a UV–visible spectrophotometer. Under aqueous conditions, the linear range of the colorimetric sensor for streptomycin and kanamycin was 1000–1,1000 and 120–480 pM, respectively. The corresponding limit of detection was 2000 pM and 120 pM, respectively. Thus, the validated dual colorimetric and ratiometric method can find various analytical applications for the ultrasensitive and rapid detection of AMG antibiotics in water samples.
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spelling pubmed-72795442020-06-15 Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin Saratale, Ganesh Dattatraya Saratale, Rijuta Ganesh Ghodake, Gajanan Shinde, Surendra Kim, Dae-Young Alyousef, Abdullah A. Arshad, Mohammed Syed, Asad Pant, Deepak Shin, Han-Seung Nanomaterials (Basel) Article Aminoglycosides (AMGs) have been extensively used to treat infectious diseases caused by Gram-negative bacteria in livestock and humans. A selective and sensitive colorimetric probe for the determination of streptomycin and kanamycin was proposed based on chlortetracycline-coated silver nanoparticles (AgNPs–CTC) as the sensing element. Almost all of the tested aminoglycoside antibiotics can rapidly induce the aggregation of AgNPs, along with a color change from yellow to orange/red. The selective detection of aminoglycoside antibiotics, including tobramycin, streptomycin, amikacin, gentamicin, neomycin, and kanamycin, with other types of antibiotics, can be achieved by ultraviolet (UV) spectroscopy. This developed colorimetric assay has ability to detect various AMGs using in-depth surface plasmon resonance (SPR) studies. With this determination of streptomycin and kanamycin was achieved at the picomolar level (pM) by using a UV–visible spectrophotometer. Under aqueous conditions, the linear range of the colorimetric sensor for streptomycin and kanamycin was 1000–1,1000 and 120–480 pM, respectively. The corresponding limit of detection was 2000 pM and 120 pM, respectively. Thus, the validated dual colorimetric and ratiometric method can find various analytical applications for the ultrasensitive and rapid detection of AMG antibiotics in water samples. MDPI 2020-05-22 /pmc/articles/PMC7279544/ /pubmed/32455981 http://dx.doi.org/10.3390/nano10050997 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Saratale, Ganesh Dattatraya
Saratale, Rijuta Ganesh
Ghodake, Gajanan
Shinde, Surendra
Kim, Dae-Young
Alyousef, Abdullah A.
Arshad, Mohammed
Syed, Asad
Pant, Deepak
Shin, Han-Seung
Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title_full Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title_fullStr Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title_full_unstemmed Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title_short Chlortetracycline-Functionalized Silver Nanoparticles as a Colorimetric Probe for Aminoglycosides: Ultrasensitive Determination of Kanamycin and Streptomycin
title_sort chlortetracycline-functionalized silver nanoparticles as a colorimetric probe for aminoglycosides: ultrasensitive determination of kanamycin and streptomycin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279544/
https://www.ncbi.nlm.nih.gov/pubmed/32455981
http://dx.doi.org/10.3390/nano10050997
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