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Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy

Digital pathology including whole slide image (WSI) acquisition is a promising tool for histopathologic teleconsultation. To test and validate the use of WSI in comparison with robotic microscopy for intraoperative frozen section consultation of peripheral hospitals serviced by our department, we co...

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Autores principales: Menter, Thomas, Nicolet, Stefan, Baumhoer, Daniel, Tolnay, Markus, Tzankov, Alexandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279565/
https://www.ncbi.nlm.nih.gov/pubmed/31719106
http://dx.doi.org/10.1136/jclinpath-2019-206261
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author Menter, Thomas
Nicolet, Stefan
Baumhoer, Daniel
Tolnay, Markus
Tzankov, Alexandar
author_facet Menter, Thomas
Nicolet, Stefan
Baumhoer, Daniel
Tolnay, Markus
Tzankov, Alexandar
author_sort Menter, Thomas
collection PubMed
description Digital pathology including whole slide image (WSI) acquisition is a promising tool for histopathologic teleconsultation. To test and validate the use of WSI in comparison with robotic microscopy for intraoperative frozen section consultation of peripheral hospitals serviced by our department, we compared the VENTANA DP 200 slide scanner with an established remote-controlled digital microscope. Thirty cases were retrospectively analysed. In comparison with a median specimen handling time of 19 min using remote-controlled microscopy, the WSI handling was significantly shorter (11 min, p=0.0089) and offered better image quality, for example, allowing to detect a positive resection margin by a malignant melanoma that had been missed using the former system. Prospectively assessed on 12 cases, the median handling time was 6 min. Here, we demonstrate the applicability and the advantages of WSI for intraoperative frozen section teleconsultation. WSI-based telepathology prooves to be an efficient and reliable tool providing superior turn-around time and image resolution.
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spelling pubmed-72795652020-06-15 Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy Menter, Thomas Nicolet, Stefan Baumhoer, Daniel Tolnay, Markus Tzankov, Alexandar J Clin Pathol Short Report Digital pathology including whole slide image (WSI) acquisition is a promising tool for histopathologic teleconsultation. To test and validate the use of WSI in comparison with robotic microscopy for intraoperative frozen section consultation of peripheral hospitals serviced by our department, we compared the VENTANA DP 200 slide scanner with an established remote-controlled digital microscope. Thirty cases were retrospectively analysed. In comparison with a median specimen handling time of 19 min using remote-controlled microscopy, the WSI handling was significantly shorter (11 min, p=0.0089) and offered better image quality, for example, allowing to detect a positive resection margin by a malignant melanoma that had been missed using the former system. Prospectively assessed on 12 cases, the median handling time was 6 min. Here, we demonstrate the applicability and the advantages of WSI for intraoperative frozen section teleconsultation. WSI-based telepathology prooves to be an efficient and reliable tool providing superior turn-around time and image resolution. BMJ Publishing Group 2020-06 2019-11-12 /pmc/articles/PMC7279565/ /pubmed/31719106 http://dx.doi.org/10.1136/jclinpath-2019-206261 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Short Report
Menter, Thomas
Nicolet, Stefan
Baumhoer, Daniel
Tolnay, Markus
Tzankov, Alexandar
Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title_full Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title_fullStr Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title_full_unstemmed Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title_short Intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
title_sort intraoperative frozen section consultation by remote whole-slide imaging analysis –validation and comparison to robotic remote microscopy
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279565/
https://www.ncbi.nlm.nih.gov/pubmed/31719106
http://dx.doi.org/10.1136/jclinpath-2019-206261
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