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Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female

Hereditary angioedema (HAE) manifests due to a deficiency of the C1-esterase inhibitor and can present with life-threatening swelling of multiple body regions such as the face, hands, upper respiratory tract, and intestinal walls. The present case describes the manifestation and symptomatic exacerba...

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Autores principales: Sankrithi, Praveen, Shah, Kunal, Bernabe, Celina C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279689/
https://www.ncbi.nlm.nih.gov/pubmed/32528748
http://dx.doi.org/10.7759/cureus.8006
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author Sankrithi, Praveen
Shah, Kunal
Bernabe, Celina C
author_facet Sankrithi, Praveen
Shah, Kunal
Bernabe, Celina C
author_sort Sankrithi, Praveen
collection PubMed
description Hereditary angioedema (HAE) manifests due to a deficiency of the C1-esterase inhibitor and can present with life-threatening swelling of multiple body regions such as the face, hands, upper respiratory tract, and intestinal walls. The present case describes the manifestation and symptomatic exacerbation of HAE in a multiparous Caucasian female. Very few trials and cases are available on HAE exacerbations during pregnancy, and our case describes the timeline and treatment in order to add to the clinical awareness of the disease. It is necessary to treat these patients rapidly to avoid unnecessary morbidity and interventions. For the time being, our patient has been appropriately managed with icatibant.
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spelling pubmed-72796892020-06-10 Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female Sankrithi, Praveen Shah, Kunal Bernabe, Celina C Cureus Allergy/Immunology Hereditary angioedema (HAE) manifests due to a deficiency of the C1-esterase inhibitor and can present with life-threatening swelling of multiple body regions such as the face, hands, upper respiratory tract, and intestinal walls. The present case describes the manifestation and symptomatic exacerbation of HAE in a multiparous Caucasian female. Very few trials and cases are available on HAE exacerbations during pregnancy, and our case describes the timeline and treatment in order to add to the clinical awareness of the disease. It is necessary to treat these patients rapidly to avoid unnecessary morbidity and interventions. For the time being, our patient has been appropriately managed with icatibant. Cureus 2020-05-07 /pmc/articles/PMC7279689/ /pubmed/32528748 http://dx.doi.org/10.7759/cureus.8006 Text en Copyright © 2020, Sankrithi et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Sankrithi, Praveen
Shah, Kunal
Bernabe, Celina C
Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title_full Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title_fullStr Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title_full_unstemmed Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title_short Pregnancy-Induced Exacerbation of Hereditary Angioedema in a Multiparous Caucasian Female
title_sort pregnancy-induced exacerbation of hereditary angioedema in a multiparous caucasian female
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279689/
https://www.ncbi.nlm.nih.gov/pubmed/32528748
http://dx.doi.org/10.7759/cureus.8006
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