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Tear Film Characteristics During Wear of Daily Disposable Contact Lenses
PURPOSE: To evaluate changes induced over time by three daily disposable (DD) contact lenses on tear meniscus height (TMH), pre-lens non-invasive break-up time (pre-lens NIBUT), tear film osmolarity (TO) and objective quality of vision (OQV). PATIENTS AND METHODS: Forty-six subjects enrolled in this...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279739/ https://www.ncbi.nlm.nih.gov/pubmed/32581509 http://dx.doi.org/10.2147/OPTH.S242422 |
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author | Montani, Giancarlo Martino, Maurizio |
author_facet | Montani, Giancarlo Martino, Maurizio |
author_sort | Montani, Giancarlo |
collection | PubMed |
description | PURPOSE: To evaluate changes induced over time by three daily disposable (DD) contact lenses on tear meniscus height (TMH), pre-lens non-invasive break-up time (pre-lens NIBUT), tear film osmolarity (TO) and objective quality of vision (OQV). PATIENTS AND METHODS: Forty-six subjects enrolled in this prospective open-label unmasked non-randomized simultaneous comparative cross-over study. For the first week of the study, subjects wore a nesofilcon A lens in the right eye and a delefilcon A lens in the left eye. After 3 days of washout, for the second week, subjects wore a nesofilcon A lens in the left eye and a stenfilcon A lens in the right eye. TMH, pre-lens NIBUT, TO and OQV were measured before contact lens fitting and for each contact lens combination on day 1 at 20 minutes and on day 7 after ≥8 hours of wear. OQV measurement included the changes of objective scatter index (OSI), the stability index (SI) and the fluctuation index (FI) calculated in a range of time of 20 s from a blink. RESULTS: TMH was unchanged at 20 minutes wear of all lenses but was significantly reduced after 8 or more hours wear (on day 7) of delefilcon A and stenfilcon A, respectively. Pre-lens NIBUT was significantly reduced with all lenses, while no significant change in TO was observed with any lens. SI and FI increased significantly for all lenses at both wear times. CONCLUSION: While the presence of any contact lens on the eye challenges the tear film, nesofilcon A contact lenses, despite their high water content, compared to delefilcon A and stenfilcon A contact lenses, showed a lower overall effect. We speculate that superior tear film behavior while wearing nesofilcon A lenses may translate to improved subjective comfort, but this remains to be evaluated. |
format | Online Article Text |
id | pubmed-7279739 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-72797392020-06-23 Tear Film Characteristics During Wear of Daily Disposable Contact Lenses Montani, Giancarlo Martino, Maurizio Clin Ophthalmol Original Research PURPOSE: To evaluate changes induced over time by three daily disposable (DD) contact lenses on tear meniscus height (TMH), pre-lens non-invasive break-up time (pre-lens NIBUT), tear film osmolarity (TO) and objective quality of vision (OQV). PATIENTS AND METHODS: Forty-six subjects enrolled in this prospective open-label unmasked non-randomized simultaneous comparative cross-over study. For the first week of the study, subjects wore a nesofilcon A lens in the right eye and a delefilcon A lens in the left eye. After 3 days of washout, for the second week, subjects wore a nesofilcon A lens in the left eye and a stenfilcon A lens in the right eye. TMH, pre-lens NIBUT, TO and OQV were measured before contact lens fitting and for each contact lens combination on day 1 at 20 minutes and on day 7 after ≥8 hours of wear. OQV measurement included the changes of objective scatter index (OSI), the stability index (SI) and the fluctuation index (FI) calculated in a range of time of 20 s from a blink. RESULTS: TMH was unchanged at 20 minutes wear of all lenses but was significantly reduced after 8 or more hours wear (on day 7) of delefilcon A and stenfilcon A, respectively. Pre-lens NIBUT was significantly reduced with all lenses, while no significant change in TO was observed with any lens. SI and FI increased significantly for all lenses at both wear times. CONCLUSION: While the presence of any contact lens on the eye challenges the tear film, nesofilcon A contact lenses, despite their high water content, compared to delefilcon A and stenfilcon A contact lenses, showed a lower overall effect. We speculate that superior tear film behavior while wearing nesofilcon A lenses may translate to improved subjective comfort, but this remains to be evaluated. Dove 2020-06-04 /pmc/articles/PMC7279739/ /pubmed/32581509 http://dx.doi.org/10.2147/OPTH.S242422 Text en © 2020 Montani and Martino. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Montani, Giancarlo Martino, Maurizio Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title | Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title_full | Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title_fullStr | Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title_full_unstemmed | Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title_short | Tear Film Characteristics During Wear of Daily Disposable Contact Lenses |
title_sort | tear film characteristics during wear of daily disposable contact lenses |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279739/ https://www.ncbi.nlm.nih.gov/pubmed/32581509 http://dx.doi.org/10.2147/OPTH.S242422 |
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