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A non-linear system patterns Rab5 GTPase on the membrane

Proteins can self-organize into spatial patterns via non-linear dynamic interactions on cellular membranes. Modelling and simulations have shown that small GTPases can generate patterns by coupling guanine nucleotide exchange factors (GEF) to effectors, generating a positive feedback of GTPase activ...

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Detalles Bibliográficos
Autores principales:	Cezanne, Alice, Lauer, Janelle, Solomatina, Anastasia, Sbalzarini, Ivo F, Zerial, Marino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279886/ https://www.ncbi.nlm.nih.gov/pubmed/32510320 http://dx.doi.org/10.7554/eLife.54434

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