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FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences
The sorting of RNA molecules to subcellular locations facilitates the activity of spatially restricted processes. We have analyzed subcellular transcriptomes of FMRP-null mouse neuronal cells to identify transcripts that depend on FMRP for efficient transport to neurites. We found that these transcr...
Autores principales: | Goering, Raeann, Hudish, Laura I, Guzman, Bryan B, Raj, Nisha, Bassell, Gary J, Russ, Holger A, Dominguez, Daniel, Taliaferro, J Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279889/ https://www.ncbi.nlm.nih.gov/pubmed/32510328 http://dx.doi.org/10.7554/eLife.52621 |
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