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Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care
Pulmonary arterial hypertension (PAH) is one of the main complications of sickle cell disease (SCD) and imparts significant risk during pregnancy. Here, we report the outcome of undetected PAH in a pregnant woman with SCD. The patient presented with severe progressive dyspnoea with echocardiographic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SMC Media Srl
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279914/ https://www.ncbi.nlm.nih.gov/pubmed/32523914 http://dx.doi.org/10.12890/2020_001532 |
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author | Karimi, Minoodokht Bavarsad |
author_facet | Karimi, Minoodokht Bavarsad |
author_sort | Karimi, Minoodokht Bavarsad |
collection | PubMed |
description | Pulmonary arterial hypertension (PAH) is one of the main complications of sickle cell disease (SCD) and imparts significant risk during pregnancy. Here, we report the outcome of undetected PAH in a pregnant woman with SCD. The patient presented with severe progressive dyspnoea with echocardiographic findings of high pressure in the pulmonary artery in the 37th week of pregnancy. Despite an emergency caesarean section, both mother and neonate died. Regular cardiovascular check-up is essential for SCD patients and careful prenatal care should include cardiovascular evaluation. PAH during pregnancy is associated with high mortality and morbidity. As there is no proof that new advanced therapies decrease the risks, early diagnosis in pregnant patients with underlying disease, like sickle cell anaemia, is essential and termination of pregnancy should be considered. LEARNING POINTS: Cardiovascular echocardiography and careful prenatal care are essential in patients with sickle cell disease. Research results should be applied to clinical practice to improve outcomes for patients with sickle cell disease. |
format | Online Article Text |
id | pubmed-7279914 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SMC Media Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-72799142020-06-09 Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care Karimi, Minoodokht Bavarsad Eur J Case Rep Intern Med Articles Pulmonary arterial hypertension (PAH) is one of the main complications of sickle cell disease (SCD) and imparts significant risk during pregnancy. Here, we report the outcome of undetected PAH in a pregnant woman with SCD. The patient presented with severe progressive dyspnoea with echocardiographic findings of high pressure in the pulmonary artery in the 37th week of pregnancy. Despite an emergency caesarean section, both mother and neonate died. Regular cardiovascular check-up is essential for SCD patients and careful prenatal care should include cardiovascular evaluation. PAH during pregnancy is associated with high mortality and morbidity. As there is no proof that new advanced therapies decrease the risks, early diagnosis in pregnant patients with underlying disease, like sickle cell anaemia, is essential and termination of pregnancy should be considered. LEARNING POINTS: Cardiovascular echocardiography and careful prenatal care are essential in patients with sickle cell disease. Research results should be applied to clinical practice to improve outcomes for patients with sickle cell disease. SMC Media Srl 2020-04-08 /pmc/articles/PMC7279914/ /pubmed/32523914 http://dx.doi.org/10.12890/2020_001532 Text en © EFIM 2020 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Articles Karimi, Minoodokht Bavarsad Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title | Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title_full | Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title_fullStr | Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title_full_unstemmed | Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title_short | Neglected Pulmonary Arterial Hypertension in Sickle Cell Anaemia during Prenatal Care |
title_sort | neglected pulmonary arterial hypertension in sickle cell anaemia during prenatal care |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279914/ https://www.ncbi.nlm.nih.gov/pubmed/32523914 http://dx.doi.org/10.12890/2020_001532 |
work_keys_str_mv | AT karimiminoodokhtbavarsad neglectedpulmonaryarterialhypertensioninsicklecellanaemiaduringprenatalcare |