D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients

The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism...

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Autores principales: Becher, Yael, Goldman, Leonid, Schacham, Nadav, Gringauz, Irina, Justo, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279916/
https://www.ncbi.nlm.nih.gov/pubmed/32523928
http://dx.doi.org/10.12890/2020_001725
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author Becher, Yael
Goldman, Leonid
Schacham, Nadav
Gringauz, Irina
Justo, Dan
author_facet Becher, Yael
Goldman, Leonid
Schacham, Nadav
Gringauz, Irina
Justo, Dan
author_sort Becher, Yael
collection PubMed
description The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients. LEARNING POINTS: The diagnosis of pulmonary embolism is challenging in COVID-19 patients since symptoms, signs and high D-dimer blood levels might be similar in both diseases. An increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.
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spelling pubmed-72799162020-06-09 D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients Becher, Yael Goldman, Leonid Schacham, Nadav Gringauz, Irina Justo, Dan Eur J Case Rep Intern Med Articles The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. We present two COVID-19 patients in whom pulmonary embolism was suspected (and diagnosed) due to a discrepancy between an increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time. We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients. LEARNING POINTS: The diagnosis of pulmonary embolism is challenging in COVID-19 patients since symptoms, signs and high D-dimer blood levels might be similar in both diseases. An increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients. SMC Media Srl 2020-05-20 /pmc/articles/PMC7279916/ /pubmed/32523928 http://dx.doi.org/10.12890/2020_001725 Text en © EFIM 2020 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Articles
Becher, Yael
Goldman, Leonid
Schacham, Nadav
Gringauz, Irina
Justo, Dan
D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_full D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_fullStr D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_full_unstemmed D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_short D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
title_sort d-dimer and c-reactive protein blood levels over time used to predict pulmonary embolism in two covid-19 patients
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279916/
https://www.ncbi.nlm.nih.gov/pubmed/32523928
http://dx.doi.org/10.12890/2020_001725
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