Cargando…

Inhibitory checkpoints in human natural killer cells: IUPHAR Review 28

Immune checkpoint inhibitors have revolutionized cancer therapy leading to exceptional success. However, there is still the need to improve their efficacy in non‐responder patients. Natural killer (NK) cells represent the first line of defence against tumours, due to their ability to release immunom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mariotti, F.R., Quatrini, L., Munari, E., Vacca, P., Tumino, N., Pietra, G., Mingari, M.C., Moretta, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	IUPHAR Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279970/ https://www.ncbi.nlm.nih.gov/pubmed/32335915 http://dx.doi.org/10.1111/bph.15081

Ejemplares similares

The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy
por: Quatrini, Linda, et al.
Publicado: (2020)

Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer
por: Sivori, Simona, et al.
Publicado: (2020)

Exploiting Human NK Cells in Tumor Therapy
por: Vacca, Paola, et al.
Publicado: (2020)

Innate Lymphoid Cells: Expression of PD-1 and Other Checkpoints in Normal and Pathological Conditions
por: Mariotti, Francesca Romana, et al.
Publicado: (2019)

Natural killer cells: From surface receptors to the cure of high‐risk leukemia (Ceppellini Lecture)
por: Falco, Michela, et al.
Publicado: (2019)

Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?
por: Tumino, Nicola, et al.
Publicado: (2020)

International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
por: Read, Cai, et al.
Publicado: (2019)

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E(2) Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions
por: Norel, Xavier, et al.
Publicado: (2020)

Polymorphonuclear Myeloid-Derived Suppressor Cells Are Abundant in Peripheral Blood of Cancer Patients and Suppress Natural Killer Cell Anti-Tumor Activity
por: Tumino, Nicola, et al.
Publicado: (2022)

An Anti-inflammatory microRNA Signature Distinguishes Group 3 Innate Lymphoid Cells From Natural Killer Cells in Human Decidua
por: Pelosi, Andrea, et al.
Publicado: (2020)

Lost in Translation (LiT)
por: Dollery, Colin T
Publicado: (2014)

International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin(1)) and GPR1 (Chemerin(2)) Nomenclature, Pharmacology, and Function
por: Kennedy, Amanda J., et al.
Publicado: (2018)

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature
por: Günther, Thomas, et al.
Publicado: (2018)

International Union of Basic and Clinical Pharmacology. CXII: Adenosine Receptors: A Further Update
por: IJzerman, Adriaan P., et al.
Publicado: (2022)

IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels
por: Harmar, Anthony J., et al.
Publicado: (2009)

The IUPHAR Pharmacology Education Project
por: Faccenda, Elena, et al.
Publicado: (2018)

Presence of innate lymphoid cells in pleural effusions of primary and metastatic tumors: Functional analysis and expression of PD‐1 receptor
por: Tumino, Nicola, et al.
Publicado: (2019)

MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells
por: Di Pace, Anna Laura, et al.
Publicado: (2023)

Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease
por: Quatrini, Linda, et al.
Publicado: (2020)

Killer Ig-Like Receptors (KIRs): Their Role in NK Cell Modulation and Developments Leading to Their Clinical Exploitation
por: Pende, Daniela, et al.
Publicado: (2019)

The IUPHAR/BPS Guide to PHARMACOLOGY in 2020: extending immunopharmacology content and introducing the IUPHAR/MMV Guide to MALARIA PHARMACOLOGY
por: Armstrong, Jane F, et al.
Publicado: (2020)

PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects
por: Munari, Enrico, et al.
Publicado: (2021)

Human Innate Lymphoid Cells: Their Functional and Cellular Interactions in Decidua
por: Vacca, Paola, et al.
Publicado: (2018)

Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma
por: Carrega, Paolo, et al.
Publicado: (2020)

BJP is linking its articles to the IUPHAR/BPS Guide to PHARMACOLOGY
por: McGrath, J C, et al.
Publicado: (2015)

The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology
por: Harding, Simon D., et al.
Publicado: (2020)

Dendritic Cell Editing by Activated Natural Killer Cells Results in a More Protective Cancer-Specific Immune Response
por: Morandi, Barbara, et al.
Publicado: (2012)

IUPHAR-DB: updated database content and new features
por: Sharman, Joanna L., et al.
Publicado: (2013)

Interaction Between MDSC and NK Cells in Solid and Hematological Malignancies: Impact on HSCT
por: Tumino, Nicola, et al.
Publicado: (2021)

Identification of neuroblastoma cell lines with uncommon TAZ(+)/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells
por: Canzonetta, Claudia, et al.
Publicado: (2021)

Stromal Cells from Human Decidua Exert a Strong Inhibitory Effect on NK Cell Function and Dendritic Cell Differentiation
por: Croxatto, Daniele, et al.
Publicado: (2014)

PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression
por: Mariotti, Francesca R., et al.
Publicado: (2018)

Environmental pharmacology—Dosing the environment: IUPHAR review 36
por: Connolly, Christopher N., et al.
Publicado: (2022)

Identification of druggable inhibitory immune checkpoints on Natural Killer cells in COVID-19
por: Demaria, Olivier, et al.
Publicado: (2020)

Inhibitory Receptors and Immune Checkpoints Regulating Natural Killer Cell Responses to Cancer
por: Buckle, Irina, et al.
Publicado: (2021)

Community guidelines for GPCR ligand bias: IUPHAR review 32
por: Kolb, Peter, et al.
Publicado: (2022)

Immune Checkpoint Blockade: A Strategy to Unleash the Potential of Natural Killer Cells in the Anti-Cancer Therapy
por: Grottoli, Melania, et al.
Publicado: (2022)

Human NK cells, their receptors and function [Image: see text]
por: Quatrini, Linda, et al.
Publicado: (2021)

NKp44-NKp44 Ligand Interactions in the Regulation of Natural Killer Cells and Other Innate Lymphoid Cells in Humans
por: Parodi, Monica, et al.
Publicado: (2019)

Heterogeneity of NK Cells and Other Innate Lymphoid Cells in Human and Murine Decidua
por: Vacca, Paola, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_smpv1ulg4i62emvfkhlda916cr