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Endobronchial tuberculosis polyps
Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobronchial i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280025/ https://www.ncbi.nlm.nih.gov/pubmed/32528684 http://dx.doi.org/10.1002/rcr2.595 |
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author | Yu, Christiaan Foo, Chuan Tai Aung, Ar Kar Joosten, Simon A. |
author_facet | Yu, Christiaan Foo, Chuan Tai Aung, Ar Kar Joosten, Simon A. |
author_sort | Yu, Christiaan |
collection | PubMed |
description | Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobronchial invasion, and nodular infiltrates in the right lower lobe. Flexible bronchoscopy revealed two endobronchial polyps at the carina and left main bronchus which were biopsied. Histopathology showed non‐caseating granulomas. Both the biopsy and bronchial washings did not identify acid‐fast bacilli on Ziehl‐Neelsen stain and had negative TB complex DNA polymerase chain reaction. One month after bronchoscopy, M. tuberculosis was cultured from the bronchial washings. Following six months of TB treatment, there was full resolution of symptoms and significant radiological improvement. We highlight the diagnostic challenges in endobronchial TB which may impact on the timely institution of treatment. |
format | Online Article Text |
id | pubmed-7280025 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-72800252020-06-10 Endobronchial tuberculosis polyps Yu, Christiaan Foo, Chuan Tai Aung, Ar Kar Joosten, Simon A. Respirol Case Rep Case Reports Endobronchial tuberculosis (TB) is an uncommon manifestation of Mycobacterium tuberculosis. We report a case of endobronchial TB polyps in a patient from India presenting with cough, loss of weight and night sweats. Computed tomography chest revealed enlarged mediastinal lymph nodes, endobronchial invasion, and nodular infiltrates in the right lower lobe. Flexible bronchoscopy revealed two endobronchial polyps at the carina and left main bronchus which were biopsied. Histopathology showed non‐caseating granulomas. Both the biopsy and bronchial washings did not identify acid‐fast bacilli on Ziehl‐Neelsen stain and had negative TB complex DNA polymerase chain reaction. One month after bronchoscopy, M. tuberculosis was cultured from the bronchial washings. Following six months of TB treatment, there was full resolution of symptoms and significant radiological improvement. We highlight the diagnostic challenges in endobronchial TB which may impact on the timely institution of treatment. John Wiley & Sons, Ltd 2020-06-08 /pmc/articles/PMC7280025/ /pubmed/32528684 http://dx.doi.org/10.1002/rcr2.595 Text en © 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Yu, Christiaan Foo, Chuan Tai Aung, Ar Kar Joosten, Simon A. Endobronchial tuberculosis polyps |
title | Endobronchial tuberculosis polyps |
title_full | Endobronchial tuberculosis polyps |
title_fullStr | Endobronchial tuberculosis polyps |
title_full_unstemmed | Endobronchial tuberculosis polyps |
title_short | Endobronchial tuberculosis polyps |
title_sort | endobronchial tuberculosis polyps |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280025/ https://www.ncbi.nlm.nih.gov/pubmed/32528684 http://dx.doi.org/10.1002/rcr2.595 |
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