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Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation
Precise gene editing aims at generating single-nucleotide modifications to correct or model human disease. However, precision editing with nucleases such as CRIPSR-Cas9 has seen limited success due to poor efficiency and limited practicality. Here, we establish a fluorescent DNA repair assay in huma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280248/ https://www.ncbi.nlm.nih.gov/pubmed/32513994 http://dx.doi.org/10.1038/s41467-020-16643-5 |