Iron overload alters the energy metabolism in patients with myelodysplastic syndromes: results from the multicenter FISM BIOFER study

Myelodysplastic syndromes (MDS) are hematological malignancies characterized by ineffective hematopoiesis and increased apoptosis in the bone marrow, which cause peripheral cytopenia. Mitochondria are key regulators of apoptosis and a site of iron accumulation that favors reactive oxygen species (RO...

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Detalles Bibliográficos
Autores principales: Cilloni, Daniela, Ravera, Silvia, Calabrese, Chiara, Gaidano, Valentina, Niscola, Pasquale, Balleari, Enrico, Gallo, Daniela, Petiti, Jessica, Signorino, Elisabetta, Rosso, Valentina, Panuzzo, Cristina, Sabatini, Federica, Andreani, Giacomo, Dragani, Matteo, Finelli, Carlo, Poloni, Antonella, Crugnola, Monica, Voso, Maria Teresa, Fenu, Susanna, Pelizzari, Annamaria, Santini, Valeria, Saglio, Giuseppe, Podestà, Marina, Frassoni, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280296/
https://www.ncbi.nlm.nih.gov/pubmed/32514107
http://dx.doi.org/10.1038/s41598-020-66162-y

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